In-vitro antibacterial activity of Cymbopogon citratus (DC.) Stapf. and Eucalyptus globulus Labill

Authors

  • Tekabe Gebre College of Veterinary Medicine and Agriculture Author
  • Getachew Addis College of Veterinary Medicine and Agriculture Author
  • Hirut Lemma Ethiopian Public Health Institute Author
  • Negero Gemeda Ethiopian Public Health Institute Author
  • Asfaw Debella Ethiopian Public Health Institute Author
  • Dinka Ayana Ethiopian Public Health Institute Author
  • Yacob Hailu Ethiopian Public Health Institute Author

Keywords:

Antibacterial activity, essential oils, medicinal plants, opportunistic bacteria, sarcoptic mange

Abstract

Background: Sarcoptic mange and associated secondary infections are challenges in improving productivity and production of goats in Ethiopia.

 

Objective: The present study has aimed at evaluating efficacy of essential oils from two plant species against opportunistic bacterial pathogens in mange infested goats.

 

Materials and methods: Essential oils (EOs) were obtained through hydrodistillation of freshly collected Cymbopogon citratus and Eucalyptus globulus leaves. Serial dilutions (20% to 0.3125%) of the EOs were tested for their antibacterial activity against Staphylococcus aureus, S. hyicus and S. intermidius using agar well diffusion and agar dilution methods and compared with standard antibiotics, erythromycin and chloramphenicol.

 

Results: Cymbopogon citratus and E. globulus EOs showed significant and dose dependent antibacterial activity. Essential oil of C. citratus was more potent than E. globulus; and S. hyicus was the most sensitive at 10% concentration. The EOs (10%) have comparable potency with the standard antibiotics. The minimum inhibitory concentration was found to be 0.125% v/v of C. citratus and 0.5% v/v of E. globulus EOs for all tested bacteria.

 

Conclusion: The two EOs showed strong antimicrobial property against the tested bacteria. However, further study is warranted to identify the specific potential EO combinations responsible for the effect, and formulation into appropriate dosage forms.

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Author Biographies

  • Tekabe Gebre, College of Veterinary Medicine and Agriculture

    College of Veterinary Medicine and Agriculture, P.O.Box 34, Bishoftu, Ethiopia

  • Getachew Addis, College of Veterinary Medicine and Agriculture

    Ethiopian Public Health Institute, P.O.Box, P.O.Box 1242, Addis Ababa, Ethiopia

  • Hirut Lemma, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, P.O.Box, P.O.Box 1242, Addis Ababa, Ethiopia

  • Negero Gemeda, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, P.O.Box, P.O.Box 1242, Addis Ababa, Ethiopia

  • Asfaw Debella, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, P.O.Box, P.O.Box 1242, Addis Ababa, Ethiopia

  • Dinka Ayana, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, P.O.Box, P.O.Box 1242, Addis Ababa, Ethiopia

  • Yacob Hailu, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, P.O.Box, P.O.Box 1242, Addis Ababa, Ethiopia

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Published

2017-11-30

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Section

Original Article

How to Cite

Gebre, T. (2017) “In-vitro antibacterial activity of Cymbopogon citratus (DC.) Stapf. and Eucalyptus globulus Labill”, Ethiopian Journal of Public Health and Nutrition (EJPHN), 2(1), pp. 3–8. Available at: https://ejphn.ephi.gov.et/index.php/ejphn/article/view/114 (Accessed: 21 May 2024).

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