Patterns of thyroid gland function and iodine level in Moringa stenopetala consuming and non-consuming areas in Southern Ethiopia

A Case-Control study

Authors

  • Asfaw Debella Ethiopian Public Health Institute Author
  • Eyasu Makonnen Addis Ababa University Author
  • Eskeziyaw Agedew Debremarkos University Author
  • Terefe Gelibo ICAPat Columbia University Author
  • Alemayehu Bekele CDT-Africa Author
  • Solomon Worku St. Paul Millennium Medical College Author
  • Ashenif Tadele Ethiopian Biodiversity Institute Author
  • Direselign Misker Arba Minch University Author
  • Yalemtsehay Mekonnen Addis Ababa University Author
  • Adamu Belay Ethiopian Public Health Institute Author
  • Feyissa Challa Ethiopian Public Health Institute Author
  • Temsgen Awoke Ethiopian Public Health Institute Author
  • Negero Gemeda Ethiopian Public Health Institute Author
  • Zeleke Geto Wollo University Author
  • Nahom Tefera Ethiopian Public Health Institute Author
  • Adisu Legesse Ethiopian Public Health Institute Author
  • Chere Tadesse Ethiopian Public Health Institute Author
  • Nigat Ashenafi Ethiopian Public Health Institute Author
  • Dawit Challa Ethiopian Public Health Institute Author
  • Seid Kassaw Ethiopian Public Health Institute Author
  • Simon Shiberu Arba Minch University Author

DOI:

https://doi.org/10.20372/ejphn.v6i2.206

Keywords:

Moringa stenopetala, case-control, thyroid gland function, iodine level

Abstract

Background: Moringa stenopetala is widely used as food, fodder and medicine in the South and South-western areas of Ethiopia. Association of M. stenopetala consumption with occurrence of goiter is still controversial. This study was aimed to investigate the association of consumption of M. stenopetala with thyroid function as well as urine iodine level, and to study iodized salt availability and utilization.

Methods: A community based unmatched case-control study was conducted from August to September, 2016. Data collection was done using WHO NCD Steps and locally constructed structured questionnaires. Physical measurements and clinical parameters were determined. Data were analyzed using SPSS version 22. Multivariate data analyses were performed to determine the associated factors based on p-value less than 0.05 and odd ratio with 95% confidence level.

Result: There was no significant difference in the mean levels of T3, T4 and TSH among case and control study participants in moringa consuming and non-consuming areas. The mean total T4 and T3 values were within the normal range of interval of the test kits. Iodized salt test indicated the presence of sufficient iodine (> 15 ppm) in more than 40% of households of the study area. Thyroid gland enlargement was not observed in the majority (> 90%) of the study participants. Urine iodine level was also normal in the majority of female participants.

Conclusion: M. stenopetala consumption did not cause significant effect on thyroid gland function and urine iodine. There was no significant association between consumption of M. stenopetala and occurrence of goiter.

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Author Biographies

  • Asfaw Debella, Ethiopian Public Health Institute

    Ethiopian Public Health Institute

  • Eyasu Makonnen, Addis Ababa University

    College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia

  • Eskeziyaw Agedew, Debremarkos University

    Debre Markos University, Debre Markos, Ethiopia

  • Terefe Gelibo, ICAPat Columbia University

    ICAP at Columbia University, Addis Ababa, Ethiopia

  • Alemayehu Bekele, CDT-Africa

    CDT-Africa, Addis Ababa, Ethiopia

  • Solomon Worku, St. Paul Millennium Medical College

    St. Paul Millennium Medical College, Addis Ababa, Ethiopia

  • Ashenif Tadele, Ethiopian Biodiversity Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Direselign Misker, Arba Minch University

    Arba Minch University, Arba Minch, Ethiopia

  • Yalemtsehay Mekonnen, Addis Ababa University

    College of Natural and Computational Sciences, Addis Ababa University, Addis Ababa, Ethiopia

  • Adamu Belay, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Feyissa Challa, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Temsgen Awoke, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Negero Gemeda, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Zeleke Geto, Wollo University

    College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia

  • Nahom Tefera, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Adisu Legesse, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Chere Tadesse, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Nigat Ashenafi, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Dawit Challa, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Seid Kassaw, Ethiopian Public Health Institute

    Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Simon Shiberu, Arba Minch University

    Arba Minch University, Arba Minch, Ethiopia

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Published

2023-07-31

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How to Cite

Debella, A. (2023) “Patterns of thyroid gland function and iodine level in Moringa stenopetala consuming and non-consuming areas in Southern Ethiopia: A Case-Control study”, Ethiopian Journal of Public Health and Nutrition (EJPHN), 6(2), pp. 85–93. doi:10.20372/ejphn.v6i2.206.

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