Patterns of biochemical markers, metabolic syndrome and their predictors among adult population in Moringa stenopetala consuming and non-consuming areas in Southern Ethiopia
A comparative cross-sectional study
DOI:
https://doi.org/10.20372/ejphn.v6i2.208Keywords:
Moringa stenopetala, multipurpose application, biochemical parameters, community-based studyAbstract
Background: Moringa stenopetala has widely been used as food for humans, feed for livestock and medicine in Southern Ethiopia. This study aimed to assess the effect of moringa in biochemical markers and risk for metabolic syndrome, in M. stenopetala consuming and non-consuming areas in Southern Ethiopia.
Methods: A comparative cross-sectional study was conducted in selected M. stenopetala consuming and non-consuming woredas, Southern Ethiopia from August to September, 2016. WHO NCD Steps and locally constructed structured questionnaires were used for data collection. Physical measurements and clinical parameters were also determined. Data were analyzed using SPSS version 22. Multivariate logistic regression analyses were performed to determine the associated factors and p-value less than 0.05considered a significant association.
Results: The normal BMI, total cholesterol, LDL and triglycerides level for moringa consuming and non-consuming participants were 84.8% versus 84.3%, 95.5% versus 92.7%, 99.3% versus 95.4% and 75% versus 81.3%, respectively. No significant change was observed in total cholesterol, HDL, LDL, triglyceride, BUN, creatinine, ALP, ALT and AST levels. On the other hand, fasting blood sugar and physical measurements i.e., BP, BMI and waist circumference also showed no significant changes in both study areas.
Conclusion: From these findings, it may be concluded that consuming M. stenopetala may not have an advantage over non-consumption in avoiding the risks of metabolic syndrome. The results of the study, however, needs to be substantiated with prospective longitudinal follow up to ascertain the effects of the frequent use of M. stenopetala.
Metrics
Downloads
References
Abrar T & Azmaxh N (2017). The miraculous moringa trees: From nutritional and medicinal point of views in tropical regions. Journal of Medicinal Plants Studies, 5(4): 151-162.
Abuye C, Urga K, Knapp H, Selmar D, Omwega AM, Imungi JK, et al. (2003). A compositional study of Moringa stenopetala leaves. East African Medical Journal, 80(5): 247-252.
Alberti KGMM, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. (2009). Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International. Circulation, 120:1640–5
Alberti G, Zimmet P, Shaw J & Grundy S (2006). International Diabetes Federation. The IDF consensus worldwide definition of the Metabolic Syndrome. International Diabetes Foundation Publication, 2: 24
Alwan A, Maclean DR, Riley LM, d' Espaignet ET & Mathers CD (2010) Monitoring and surveillance of chronic non-communicable diseases: progress and capacity in high-burden countries. Lancet, 376: 1861- 1868.
Tekle A, Belay, A, Kelem K, W/Yohannes M, Woda B, Tesfaye Y, et al. (2013). Nutritional profile of Moringa stenopetala species samples collected in different places in Ethiopia and their comparison with Moringa oleifera species, a paper presented in NNP launch workshop, 24th -27th June 2013, Hilton Hotel, Addis Ababa. European Journal of Nutrition and Food Safety, 5(5): 1100-1101
Berger, M.R., Habs, M., Jahn, SA. and Schmahl D. (1984). Toxicological assessment of seeds from Moringa oleifera and Moringa stenopetala, two highly efficient primary coagulants fordomestic water treatment of tropical raw waters. East African Medical Journal, 61(9): 712-6.
Cocchini M, Sassi F, Laucer J, Lee Y, Guajardo-Barron V & Chisholm D (2010). Tracking of unhealthy diets, physical inactivity and obesity. Health effects and cost effectiveness. The lancet, 376 (9754), 1775-1784
Demeulenaere E (2001). E. Moringa stenopetala; a subsistence resource in the Konso district. Development potential of Moringa products. In: Proceedings of a workshop, 29 October -2 November 2001, Dar es Salaam, Tanzania.
Ghebreselassie D, Mekonnen Y, Gebru G, Ergete W & Huruy K (2011). The effects of Moringa stenopetala on blood parameters and histopathology of liver and kidney in mice Ethiop. Journal of Health Development, 25 (11): 51-57.
Geleta B, Eyassu M, Fekadu N, Debella A & Challa F (2015). Evaluation of diuretic activity of hydro-ethanolic extract of Moringa stenopetala in Swiss Albino Mice. Clinical and Experimental Pharmacology, 5(5): 1-5.
Geleta B, Mekonnen E, Debella A & Tadele A (2016A). In vivo antihypertensive and antihyperlipidemic effects of the crude extracts and fractions of Moringa stenopetala (Baker f.) Cufod. leaves in rats. Frontiers in Pharmacology, 7: 1-10.
Geleta B, Mekonnen E, Debella A, Abebe A & Fekadu N (2016B). In vitro vasodilatory activity and possible mechanism of the crude extracts and fractions of Moringa stenopetala (Baker f.) Cufod. leaves in isolated thoracic aorta of guinea pigs. Journal of Experimental Pharmacology, 8: 35-42.
Hassen AM, Reddy PV & Debella A (2014). Acute and sub-chronic toxicity studies of butanol fraction of leaves of Moringa stenopetalaon some blood parameters and histopathology of liver and kidney in rats, of aqueous extract of Moringa stenopetalain both in vivo and in vitro animal models. Asian Pacific Journal of Health Sciences, (2): 160-164.
Ichihara K (2014). Statistical considerations for harmonization of the global multicenter study on reference values. International Journal of Clinical Chemistry and Diagnostic Laboratory Medicine, 432:108–18
Katayev A, Balciza C & Seccombe DW (2010). Establishing Reference Intervals for Clinical Laboratory Test Results Is There a Better Way? American Journal of Clinical Pathology, 133:180 - 186
Lozano R., Naghavi M, Formen K, Lim S, Shibuya & Aboyans V (2012). Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systemic analysis for the Global Burden of Disease Study. Lancet, 380: 2095-128.
Löhr B, El-Samalouti V, & Junge WL (2009). Reference Range Study for Various Parameters on Roche Clinical Chemistry Analyzers. Clinical Laboratory, 55:465-471
Mekonnen Y & Gessesse A (1998). Documentation on the uses of Moringa stenopetala and its possible antileishmanial and antifertility effects. SINET: Ethiopian Journal of Science,21: 287-295.
Makonnen E, Hunde A & Damecha G (1997). Hypoglycemic effect of Moringa stenopetala aqueous extracts in rabbits. Phytotherapy Research, 11: 147-148.
Makkar LM & Becker K (1997). Nutrients and antiquality factors in different Morphological parts of the Moringa oleifera tree.Journal of Agricultural Science, 128: 311-322.
Mengistu M, Abebe Y, Mekonnen Y & Tolessa T (2012). In vivo and in vitro hypotensive effect of aqueous extract of Moringa stenopetala. African Health Sciences, 12(4): 545-551.
Mussa A, Makonnen E & Urga K (2008). Effects of the crude aqueous exract and isolated fraction ofMoringastenopetala leaves in normal and diabetic mice. Pharmacologyonline (3): 1049-1055.
Musa AH, Vata PK, Gebru G, Mekonnen Y, Debella, A & Makonnen E (2015). Sub-chronicToxicity studies of butanol fraction of leaves of Moringa stenopetala in experimental rats. International Journal of Current Medical and Pharmaceutical research, 1(10):170-175.
Nardos A, Makonnen E & Debella A (2011). Effects of crude extracts and fractions of Moringa stenopetala (Baker f) Cufodontis leaves in normoglycemic and alloxan-induced diabetic mice. African Journal of Pharmacy and Pharmacology, 5(20): 2220-28.
Nauk M Wiebe D & Warnick G (2004). Measurement of High-Density- Lipoprotein Cholesterol. 221-244. In: Handbook of Lipoprotein Testing (eds. Rifai, Warnick and Dominiczak), 2nd edition.
Padayachee B & Baijnath H (2012). An overview of the medicinal importance of Moringaceae. Journal of Medicinal Plants Research, 6(48):5831-5839.
Rifai N, Warnick GR & McNamara JR (1992). Measurement of Low- Density-Lipoprotein Cholesterol in Serum: a Status Report. Clinical Chemistry, 1992; 38:150-160
Sileshi T, Makonnen E, Debella A & Tesfaye B (2014). Antihyperglycemic and sub-chronic toxicity study of Moringa stenopetalaleaves in mice. Journal of Coastal Life Medicine, 2(3): 214-221.
Shah RV, Murthy VL, Abbasi SA, Blankstein R, Kwong RY, Goldfine AB, et al. (2014). Visceral Adiposity and the Risk of Metabolic Syndrome a Cross Body Mass Index: The MESA Study. Cardiovasc Imaging. Journal of the American College of Cardiology, 7:1221–35.
Toma A, Makonnen E, Mekonnen Y, Debella A & Adisakwattana S (2016). Antidiabetic activities of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozotocin-induced diabetic rats. BMC Complementary Medicine and Therapies, 15(242): 1-8
Wu AHB, ed. Tietz Clinical Guide to Laboratory Tests (2006). 4th edition. St. Louis (MO): Saunders Elsevier, 1096: 1798.
Yang R, Chang L, Hsu J, Weng BBC, Palada MC, Chadha ML & Levasseur V (2006). Moringa and Other Highly Nutritious Plant Resources: Strategies, Standards and Markets for a Better Impact on Nutrition in Africa. Accra, Ghana, Pp 1–9.
Downloads
Published
License
Copyright (c) 2024 Ethiopian Journal of Public Health and Nutrition (EJPHN)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This work is licensed under GNU General public license.
How to Cite
